Whatever the majority wants is fine but injuries are what makes building a complete roster difficult & important.
I run a league (Death & Destruction) that uses zero injuries and only 30 of tge 53 players on the roster ever see the field since zero injuries means you can set fatigue to 100% across the board if you want and never worry.
It's fun in its own way but it also means owners can use 2-3 playmakers on offense to put up ridiculous stats.
Below is some examples from that league with zero injuries.
I know we are discussing lowering it to somewhere between 50-74, not 0 but my point is the lower the injury rate, the more dominant owners will dominate. It's a simple fact!!!
Chose wisely my friends