Are exist some deffensive plays which 100% will beat some offensive play?
Spam 4-3 Under Double LB blitz, Nickle Strong CB3 Blitz Double LB Blitz, Dime SS MLB Blitz, and 46 SS MLB blitz against GL offenses. That should do it.
Are exist some deffensive plays which 100% will beat some offensive play?
No, and there shouldn't be. Now if you are talking about a specific play then you should be using plays that put your defenders in the best position to counter what the offense is doing.